Assayed purity
What this measured
Beta anomer specifically — the alpha form is biologically inactive, and purity assays that do not distinguish the two tell you nothing.
Single Ingredient
1 / 5Consumable · Cellular Energy
β-NMN at 99.9% purity. One capsule, one ingredient.
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$1.53 a day
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The Evidence
Assayed purity
Beta anomer specifically — the alpha form is biologically inactive, and purity assays that do not distinguish the two tell you nothing.
Trial participants1
Randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent design over sixty days.
Ingredient
β-NMN in a vegetable capsule. Nothing added to pad the label.
Mechanism
Figures describe research on individual ingredients rather than on this finished product. Sources and the full disclosure are at the foot of the page.
The Formulation Story
Formulated for
The Formulation
Every active, named. Consumable doses are printed to the milligram on the label. For topicals, actives are listed in order of concentration — and where a number cannot be independently verified, we do not print one.
Serving size
One capsule, morning
30 capsules · 30 days
500 mg per capsule. The immediate biosynthetic precursor to NAD⁺ — one enzymatic step away. Beta anomer, at 99.9% assayed purity.
500 mgPlant-derived capsule shell. Vegan and halal certified.
The Protocol
Consistency is the variable that decides outcomes. Build the habit first; the biology follows on its own schedule.
With 6–8 oz of water. NAD⁺ metabolism is circadian; morning dosing aligns with the natural peak.
The trial dosed daily for sixty days and measured at thirty and sixty. Consistency is the mechanism.
This is not a stimulant. If you are looking for something you feel within the hour, you have the wrong compound.
Nothing perceptible
Substrate pools are refilling. There is no acute sensation, and a product that produces one is doing something other than this.
First measurement point
Blood NAD concentrations were significantly elevated versus placebo and baseline at this point in the trial.
Full trial endpoint
NAD concentrations highest at the upper doses, and six-minute walk distance significantly greater than placebo.
Individual variation
Response differs substantially between people — follow-up analysis reported a coefficient of variation between 29% and 113%. Nobody can currently predict who responds most.
Questions
Both raise NAD⁺, and no adequately powered head-to-head trial in humans has established one as superior. NMN is one enzymatic step from NAD⁺; NR is two. We chose NMN on the directness of the pathway and the quality of the recent dose-ranging work. Anyone telling you the question is settled is overstating the evidence.
Probably not, and we would be suspicious of a product that produced an acute sensation. NMN works by replenishing a substrate pool over weeks. The trial measured blood NAD and walking distance, not subjective energy. Some people report improved stamina after several weeks; a substantial number report nothing at all. Both are consistent with the data.
Because only the beta form is biologically active. Alpha-NMN is inert. A purity figure that does not distinguish between them is not telling you anything useful — which is precisely why cheap NMN can show impressive-looking assay numbers and do nothing.
In the sixty-day randomized trial, NMN was well tolerated at all doses with no significant safety signals. Longer human data are limited — the trials have not run long enough to answer multi-year questions. We think it is a reasonable compound to take and we think anyone claiming the long-term picture is complete is going beyond the evidence.
It does not matter much. Take it with water in the morning, with or without breakfast, and take it consistently. Consistency matters considerably more than timing.
References
For anyone who wants to read further.
Please note — These references describe studies of individual ingredients, not of this finished product. They are provided for educational purposes and do not constitute a claim that this product produces the same result. These statements have not been evaluated by the Food and Drug Administration.